Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

Some of our most fundamental moral rules are violated by the practices of torture and war. If one examines the concrete forms these practices take, can the exceptions to the rules necessary to either torture or war be justified? Fighting Hurt brings together key essays by Henry Shue on the issue of torture, and relatedly, the moral challenges surrounding the initiation and conduct of war, and features a new introduction outlining the argument of the essays, putting them into context, (...) and describing how and in what ways his position has modified over time. The first six chapters marshal arguments that have been refined over 35 years for the conclusion that torture can never be justified in any actual circumstances whatsoever. The practice of torture has nothing significant in common with the ticking bomb scenario often used in its defence, and weak U.S. statutes have loop-holes for psychological torture of the kind now favoured by CIA in the 'war against terrorism'. The other sixteen chapters maintain that for as long as wars are in fact fought, it is morally urgent to limit specific destructive practices that cannot be prohibited. Two possible exceptions to the UN Charter's prohibition on all but defensive wars, humanitarian military intervention and preventive war to eliminate WMD, are evaluated; and one possible exception to the principle of discrimination, Michael Walzer's 'supreme emergency', is sharply criticized. Two other fundamental issues about the rules for the conduct of war receive extensive controversial treatment. The first is the rules to limit the bombing of dual-use infrastructure, with a focus on alternative interpretations of the principle of proportionality that limits 'collateral damage'. The second is the moral status of the laws of war as embodied in International Humanitarian Law. It is argued that the current philosophical critique of IHL by Jeff McMahan focused on individual moral liability to attack is an intellectual dead-end and that the morally best rules are international laws that are the same for all fighters.Examining real cases, including U.S. bombing of Iraq in 1991, the Clinton Administration decision not to intervene in the 1994 Rwandan genocide, NATO bombing of Serbia in 1999, and CIA torture after 9/11 and its alternatives, this book is highly accessible to general readers who are interested in the ethical status of American political life, especially foreign policy. (shrink)

It has been said that those who do not remember the past are condemned to repeat it. It is important, therefore, to consider the parallels between the decimation of basic and applied biology by Trofim Denisovich Lysenko in the Soviet Union earlier in this century and the battering of present-day biotechnology by the Clinton administration. In both cases, we see the sacrifice of new science to old myth; heterodox, unscientific theories steering public policy; the abject failure of that public (...) policy, with dire outcomes for research and commerce; and glib, condescending, and exclusionary attitudes toward policymaking. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Literature 25.2 (2001) 373-376 [Access article in PDF] Book Review Why Literature Matters: Permanence and the Politics of Reputation Why Literature Matters: Permanence and the Politics of Reputation, by Glenn C. Arbery; 255 pp. Wilmington, Delaware: ISI Books, 2001, $24.95. Over the last decade or so, there has appeared an increasing number of books critical of the profession of literary studies. Such criticism has typically been directed (...) at literary theory and its preoccupation with the politics of race, class, and gender. To a limited extent, Glenn Arbery's Why Literature Matters: Permanence and the Politics of Reputation can be classified as belonging to such a "genre." Early in the book, for example, Arbery argues in favor of the "old-fashioned" idea, as he calls it, that literature is a "mode of knowledge" with the potential to open up transcendent modes of experience. Yet Why Literature Matters is so short on polemics and so long on incisive, sometimes brilliant readings of works ranging from the poetry and fiction of Seamus Heaney, Tom Wolfe, Toni Morrison, and Emily Dickinson to Shakespeare's Othello and Homer's Iliad, that such a characterization is insufficient at best and distorting at worst. Notwithstanding its title, this book is devoted less to advancing a polemic about "why literature matters" than to dramatizing, with performative power and grace, why most of us, politically oriented or not, are already quite sure that it does.Such performative power can be felt throughout Why Literature Matters, but [End Page 373] its presence is especially strong in the final, lengthy chapter on the Iliad, "The Sacrifice of Achilles." Bringing to bear his training as a classical scholar, Arbery contends that the Iliad is "about" a single event: the death or "sacrifice" of Achilles. Achilles, Arbery notes, was not just the greatest hero of the Iliad. He was also the greatest hero of the entire classical world: "Achilles has no rival in glory, either in the generation of heroes before him (not even Herakles), or in the ages after him. According to Plutarch, Julius Caesar wept because he had not accomplished as much as Alexander at the same age, but Alexander the Great envied Achilles."Why, then, does Arbery refer to Achilles' death as "sacrificial"? Drawing on a version of the Greek myth whose source is Pindar rather than the more commonly cited Hesiod, Arbery observes that Achilles' sacrificial death, which is not in fact narrated in the Iliad but is everywhere taken for granted, was necessitated by Zeus' successful plan to forestall a prophecy. That prophecy said that a son would be born to Zeus and the goddess Thetis, who would overthrow the Olympian god as Zeus had overthrown the Titans. Such a son, prophesized to be not the greatest of mortals but, much more, the greatest of gods, would have been--should have been, from Achilles's justly embittered standpoint--Achilles. But in fact Zeus foiled the prophecy by marrying Thetis off to a mere mortal, Peleus, thereby ensuring his own continued reign and Achilles' eventual death.It is the burden of Arbery's discussion to show not just that Achilles comes to accept and even "will" his own death, but that the meaning of such sacrificial death is embodied and given "presence" in the poetic form and language of the Iliad, including especially the descriptions of Patrocles and Hector, each of whom "inhabits the meaning of Achilles" by dying, successively, in Achilles' armor. Arbery goes so far as to compare Achilles' sacrifice with Christ's, asserting that reading the Iliad "in ignorance of the central importance of the marriage of Peleus and Thetis [is comparable] to reading [Dante's] Inferno (where references to holy things are scarce) in ignorance of the existence of Christ."Arbery makes clear, however, that it is the differences, rather than the similarities, that are most important in such a comparison. Those differences revolve around three issues. First, whereas Christ is a deity who sacrifices himself for humanity, Achilles is a mortal who sacrifices himself for the gods. Second, whereas humanity gains ultimate... (shrink)

Perhaps only Tar Baby is as enigmatic and compelling a figure from Afro-American mythic discourse as is that oxymoron, the Signifying Monkey.3 The ironic reversal of a received racist image of the black as simianlike, the Signifying Monkey—he who dwells at the margins of discourse, ever punning, ever troping, ever embodying the ambiguities of language—is our trope for repetition and revision, indeed, is our trope of chiasmus itself, repeating and simultaneously reversing in one deft, discursive act. If Vico and Burke, (...) or Nietzsche, Paul de Man, and Harold Bloom, are correct in identifying “master tropes,” then we might think of these as the “master’s tropes,” and of signifying as the slave’s trope, the trope of tropes, as Bloom characterizes metalepsis, “a trope-reversing trope, a figure of a figure.” Signifying is a trope that subsumes other rhetorical tropes, including metaphor, metonymy, synecdoche, and irony, and also hyberbole, litotes, and metalepsis. To this list, we could easily add aporia, chiasmus, and catachresis, all of which are used in the ritual of signifying.The black tradition has its own subdivisions of signifying, which we could readily identify with the typology of figures received from classical and medieval rhetoric, as Bloom has done with his “maps of misprision.” In black discourse “signifying” means modes of figuration itself. When one signifies, as Kimberly W. Benston puns, one “tropes-a-dope.” The black rhetorical tropes subsumed under signifying would include “marking,” “loud-talking,” “specifying,” “testifying,” “calling out”, “sounding,” “rapping,” and “playing the dozens.”4 3. On Tar Baby, see Ralph Ellison, “Hidden Man and Complex Fate: A Writer’s Experience in the United States,” Shadow and Act, p. 147, and Toni Morrison, Tar Baby. On the black as quasi-simian, see Jean Bodin, Method for the Easy Comprehension of History, trans. Beatrice Reynolds, p. 105; Aristotle Historia Animalium 606b; Thomas Herbert, Some Years Travels, pp. 16-17; and John Locke, An Essay Concerning Human Understanding, 8th ed., 2 vols., 2:53.4. Geneva Smitherman defines these and other black tropes and then traces their use in several black texts. Smitherman’s work, like that of Claudia Mitchell-Kernan and Abrahams, is especially significant for literary theory. See Smitherman, Talkin and Testifyin: The Language of Black America, pp. 101-66. See also nn. 13 and 14 below. (shrink)

Michael Ryan's Literary Theory: A Practical Introduction, Second Edition introduces students to the full range of contemporary approaches to the study of literature and culture, from Formalism, Structuralism, and Historicism to Ethnic Studies, Gender Studies, and Global English. Introduces readings from a variety of theoretical perspectives, on classic literary texts. Demonstrates how the varying perspectives on texts can lead to different interpretations of the same work. Contains an accessible account of different theoretical approaches An ideal resource for use in introductory (...) courses on literary theory and criticism. Designed to function both as a stand-alone text and a companion to Rivkin and Ryan’s Literary Theory: An Anthology, Second Edition. (shrink)

So considered, Hume is viewed as a naturalist, whose project in the first three parts of the first book of the Treatise is to provide an account of the ...

CHAPTER I GENERAL ACCOUNT OF THE SUBJECT THERE is some difficulty in defining the subject of Ethics in a manner which can fairly claim general acceptance ...

Book reviewed in this article: Clinical Ethics: A Practical Approach to Ethical Decisions in Clinical Medicine. By Albert R. Jonsen, Mark Siegler, and William J. Winslade.

The original text, written in the language and style of 1909, is almost completely unreadable in 2011. I have taken the liberty of editing it and paraphrasing it for the sake of readability; I have made every effort to preserve the author’s original meaning. Section headings and tables have been added by Prof. Steinhart. Note that Figure 1 is by Adams.

Christof Koch and Klaus Hepp, in a recent essay in this journal1, issued a challenge to “those who call upon consciousness to carry the burden of the measurement problem in quantum mechanics.” Lest absence of a response be construed as admission of a failure of the idea that consciousness can play, via quantum measurement effects, a crucial role in neurodynamics, or that this idea has been in any rational way damaged by the arguments put forth in the cited article, I (...) respond here to that challenge. (shrink)

Levinas is a thinker for the future, concerned with the future. He inverts the priority of the declaration of the French Revolution "Freedom, Equality, Brotherhood", by designating "brotherhood" first among modern European society's most cherished values. Levinas sees brotherhood as the fundamental condition of our shared humanity and as the foundation of freedom and equality. Thus, he presents himself as a Western thinker who sets modern thought on its head and at the same time enriches it. His radical view of (...) the other, responsibility, subjectivity and the Infinite remains a challenge, today more than ever. Calling out to both religious and secular seekers alike, Levinas asks for an alert and critical dialogue of the ethical and metaphysical meaning of our inter-human and social relationships. In this work, a new generation of philosophers, ethicists and theologians embark on a conversation with Levians, with due appreciation for his genius and uninhibitedness in their questioning. The intermediaries in this provocative dialogue are: Hannah Arendt, Henri Bergson, Anders Nygren, Paul Ricoeur and Hans Urs von Balthasar. The following themes are thus treated: - ethics as liberation and redemption beyond the self - time, duration and alterity - freedom, society and politics - desire between eros and agape - 'good enough' parenting and family ethics - conversational processes and pastoral counselling - asymmetry and reciprocity between the self and the other - modern humanism vs. post-modern anti-humanism as an inspiration for a renewed secular humanism - suffering, death and euthanasia - perspectives and boundaries of interreligious dialogue - the (im)possibility of a Christian interpretation of Levinas' Jewish-inspired thought - a new Christian theology of Trinitarian praxis. This volume likewise includes contributions by: Roger Burggraeve, W. Wolf Diedrich, Annemie Dillen, Thomas Folens, Glen Morrison, Marianne Moyaert, Marina Riemslagh, Anya Topolski, Emilie Van Daele, Jean Vanheessen, Sophie Veulemans and Torben Wolfs. In this book Levinas is presented as an 'extra-ordinary' other who awakes into vigilance the conscience of not only the contributors, but the readers as well: one speaks and the other responds differently. (shrink)

First published in 1993. Routledge is an imprint of Taylor & Francis, an informa company.

This is an exploration of what Locke and Whately said about the Argumentatum ad Hominem, especially in the context of what they said about the other ad arguments, and with a view to ascertaining whether what they said lends support to the understanding of this argument implicit in Johnstone's thesis that all valid philosophical arguments are ad hominem. It is concluded that this support is forthcoming insofar as Locke and Whately had in mind an argument concerned with principles.The essay ends (...) with a brief reformulation of Johnstone's generalization regarding philosophical arguments. (shrink)

The original text, written in the language and style of 1904, is almost completely unreadable in 2011. I have taken the liberty of editing it and paraphrasing it for the sake of readability; I have made every effort to preserve the author’s original meaning. Section headings have been added by Prof. Steinhart.

It is emphasized that a many-worlds interpretation of quantum theory exists only to the extent that the associated basis problem is solved. The core basis problem is that the robust enduring states specified by environmental decoherence effects are essentially Gaussian wave packets that form continua of non-orthogonal states. Hence they are not a discrete set of orthogonal basis states to which finite probabilities can be assigned by the usual rules. The natural way to get an orthogonal basis without going outside (...) the Schroedinger dynamics is to use the eigenstates of the reduced density matrix, and this idea is the basis of some recent attempts by many-worlds proponents to solve the basis problem. But these eigenstates do not enjoy the locality and quasi-classicality properties of the states defined by environmental decoherence effects, and hence are not satisfactory preferred basis states. This core problem is obscured by approaches that treat the universe as a quantum computer, but it needs to be addressed and resolved before a many-worlds-type interpretation can be said to exist. (shrink)

Henry Home (1696-1782) has been called "perhaps the most complete 'Enlightenment man' among the eighteenth-century Scottish thinkers." Kinsman and friend of David Hume, mentor and patron of Adam Smith, John Millar, and Thomas Reid, he was a key figure in that circle of luminaries. He read law, was called to the bar in 1723, was raised to the Bench of the Court of Session in 1752, with the title Lord Kames (the name of his family estate), and joined the (...) High Court of the Justiciary in 1763. Publishing broadly in law, history, philosophy, and criticism, Kames made significant contributions to the Enlightenment's science of human nature. The Essays is commonly considered Kames's most important philosophical work. In the first part, he sets forth the principles and foundations of morality and justice, attacking Hume's moral skepticism and addressing the controversial issue of the freedom of human will. In the second part, Kames focuses on questions of metaphysics and epistemology to offer a natural theology in which the authority of the external senses is an important basis for belief in the Deity. The text of this volume is based on the third edition of 1779, while the appendix presents substantial variant readings in the first and second editions. (shrink)

Introduction.--The Puritan heresy.--Emerson.--Paul Elmer More.--William James.--John Dewey.--Nietzsche.--Bergson.--The limitations of Marxism.--T. S. Eliot.--Christopher Dawson.--Kenneth Burke.--Jeffersonian democracy.